Gallbladder microbiota in laboratory animals: Insights and implications

Gallbladder microbiome in laboratory animals




Gallbladder microbiome, mice, rabbit, microbiota


The aim of this review is to give novel information about the gallbladder microbiome's clinical importance and alteration of the gallbladder microbiota of specific laboratory animals in health and disease. The significant involvement of the gastrointestinal microbiota (GM) in maintaining optimal health has been widely acknowledged. Their functions include a broad spectrum of mechanisms, such as facilitating digestion, enhancing the immune system and strengthening against bacterial pathogens and pathogenic commensal microorganisms. Until now, the majority of research on bacterial function and diversity has concentrated on the colon due to its easy accessibility for sample collection and the abundant presence of bacteria in that region. Despite the widespread interest in examining how the intestinal microbiota affects health and disease, it is unexpected that there has been a inadequate number of researchs focusing on investigating the microbial structure of bile. The gallbladder microbiome, although often neglected in human medicine, is a valuable source of discovery for veterinarians. Its applicability, especially in laboratory animals and hospitalized small animal patients, shows the prospective value of investigating the gallbladder microbiome as an encouraging avenue in the scope of veterinary medicine. Research in this field reveals important insights that can enrich veterinary clinical practice and offer new perspectives on animal health.


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How to Cite

Tendar, İlayda, Erdoğan, H., Erdoğan, S., & Ural, K. (2023). Gallbladder microbiota in laboratory animals: Insights and implications: Gallbladder microbiome in laboratory animals. Rats, 1(2), 35–39.