Successful surgical management of fibroma tumor in rats
DOI:
https://doi.org/10.5281/zenodo.18094647Keywords:
Fibroma, geriatrics, male, Wistar strainAbstract
An adult male Wistar rat, aged two years, presented with an abnormal growth in the central abdominal region. Surgical treatment was performed under general anesthesia, involving excision of the mass. Histopathological examination diagnosed a fibroma, characterized by the presence of coarse bundles of collagen fibers interspersed with individual fibroblasts. Hematological evaluation included measurements of red blood cell count (RBC), white blood cell count (WBC), hemoglobin concentration (HBG), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and platelet count (PLT). All parameters were generally within physiological reference ranges. In our case,, the aged male Wistar rat, underwent successful surgical treatment for a spontaneous benign fibroma during healthy aging, ultimately improving physiological comfort and recovery. There is a lack of published studies addressing this issue, which could shed light on the frequency of fibroma occurrence in rats across different strains and age groups.
References
1. Llera R, Stoewen D, Pinard C. Benign Fibrous Skin Tumors &VCA Animal Hospitals. Available:[https://vcahospitals.com/know-your-pet/fibrous-tumors-benign-and-hamartomas#],visited: [24. 08. 2025. 00:48], 2025.
2. Ufaysa GG, Jiregna D. Diagnosis and surgical management of hard fibroma in a bullock.” Journal of Veterinary Medicine and Science, 2025; 2(1); DOI:10.61148/JVMS/012
3. Kumar KM, Rao ChM, Veena P, Amrita V, Reddy KS, Kumari DV, Baba MS. Surgical Management of Fibroma in a Bullock: A Case Report. International Journal of Science Environment and Technology. 2014; 3(6): 2284-2286.
4. John M, Chirayath S, Paulson S. Multiple soft fibromas of the lid. Indian Journal of Ophthalmology. 2015; 63(3): 262-264. DOI: 10.4103/0301-4738.156932
5. Castaneda JB, MacDougall DB, . Hogan BP. Sporadic sclerotic fibroma of the tongue: A rare case. J Oral Maxillofac Surg Med Pathol. 2016. http://dx.doi.org/10.1016/j.ajoms.2016.01.005
6. Kahraman D, Karakoyunlu B, Karagece U, Ertas U, Gunhan O. Desmoplastic fibroma of the jaw bones: A series of twenty-two cases, Journal of Bone Oncology. 2020. doi: https://doi.org/10.1016/j.jbo.2020.100333
7. Cornell Wildlife Health Lab. Fibromas. Available:[https://cwhl.vet.cornell.edu/disease/fibromas], visited: [24. 08. 2025. 02:39], 2025.
8. Raayat JA, Tabatabaei A, Khoda KTA, Mehrshad S, Ghalebi R. 2008. Cutaneous fibroma and its surgical excision in a horse. Iranian Veterinary Surgery Association (IVSA). 2008; 3(1):101-105.
9. Alsobayil FA. and El-Amir YO. Throughout Pathological Study on Skin, Subcutaneous and Mucosal Neoplasia of the Dromedary Camel. Brazilian Journal of Veterinary Pathology, 2013; 6:48-55.
10. Hasan MM. Surgical Management of Fibroma in an Indigen. Chattogram Veterinary & Animal Sciences University, Khulshi, Chattogram. 2023.
11. Villalobos AE. Connective Tissue Tumors in Animals. MSD Manual Veterinary Manual. Available:[https://www.msdvetmanual.com/integumentary-system/tumors-of-the-skin-and-soft-tissues/connective-tissue-tumors-in-animals], visited:[24.08.2025.02:50], 2025.
12. Parmar JJ, Parray AH, Shah AI, Rao N, Godasara DJ. Successful Surgical Management of Tumours in Rats. Int.J.Curr.Microbiol.App.Sci. 2020; 9(9): 2118-2121. doi: https://doi.org/10.20546/ijcmas.2020.909.264
13. Raja Ramesh GV. Types of Cancer and Surgery in Rats (Rattus norvegicus). Research & Reviews: Journal of Veterinary Sciences, 2016; 3(1): 4-9.
14. Poteracki J, Walsh KM. Spontaneous Neoplasms in ControlWistar Rats: A Comparison of Reviews. Toxicological Sciences, 1998;45: 1-8.
15. Madheswaran R, Srinivasan MR, Sivaseelan S, Balasubramaniam GA, Arulmozhi A, Balachandran P. Mammary adenocarcinoma in Wister rat- A case report. Indian Journal Veterinary Pathology. 2014; 38(2): 128-130.
16. Millán Y, Sánchez-Céspedes R, Moyano R, Ayala N, Molina-López A. Spontaneous fibroadenoma in a twenty-one-week-old female Wistar rat –a case report. Veterinarski Arhiv, 2023; 93(5): 601-608.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Rats

This work is licensed under a Creative Commons Attribution 4.0 International License.

















